LITTLE KNOWN FACTS ABOUT PHENOBARBITAL SODIUM WATER SOLUBILITY.

pentobarbital decreases effects of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of CYP3A4 inducers could lessen sufentanil concentrations and efficacy, maybe precipitating withdrawal syndrome in clients who definitely have designed Bodily dependence to sufentanil.